Rohu Fish (Labio Rohita) Bile Attenuates Streptozotocin- Induced Diabetes Mellitus in Rats: Evidence from Biochemical and Oxidative Stress Markers

Diosgenin attenuates cardiac oxidative stress in streptozotocin- induced diabetic rat

Background and Objective: Chronic diabetes mellitus (DM) leads to cardiovascular dysfunction. Diosgenin is a natural steroidal saponin with cardiovascular protective potential. In this research study, the beneficial effect of diosgenin was evaluated on some markers of oxidative stress in cardia tissue of streptozotocin (STZ)-diabetic rats. Materials and Methods: Male Wistar rats (n = 28) were ...

Mulberry Leaf Extract Attenuates Oxidative Stress-Mediated Testosterone Depletion in Streptozotocin-Induced Diabetic Rats

Background: It has been proposed that oxidative stress may contribute to the development of testicular abnormalities in diabetes. Morus alba leaf extract (MAE) has hypoglycemic and antioxidant properties. We, therefore, explored the impact of the administration of MAE on steroidogenesis in diabetic rats. Methods: To address this hypothesis, we measured the serum level of glucose, insulin, and f...

Centella asiatica Ameliorates Diabetic Complications and Oxidative Stress in Streptozotocin - Induced Diabetes Mellitus in Male Rats

Effects of Centella asiatica upon oxidative stress and dysfunctions of liver, heart, kidney and testis in STZ-diabetic rats were investigated. Animals were divided into four groups Group 1, Control; Group 2, streptozotocin (STZ); Group 3, C. asiatica treated plus streptozotocin and Group 4, C. asiatica. Toxicological parameters including AST, ALT, ALP, LDH and CK-MB were significantly improved ...

diosgenin attenuates cardiac oxidative stress in streptozotocin- induced diabetic rat

background and objective: chronic diabetes mellitus (dm) leads to cardiovascular dysfunction. diosgenin is a natural steroidal saponin with cardiovascular protective potential. in this research study, the beneficial effect of diosgenin was evaluated on some markers of oxidative stress in cardia tissue of streptozotocin (stz)-diabetic rats. materials and methods: male wistar rats (n = 28) were d...

the sesame lignan sesamin attenuates vascular permeability in rats with streptozotocin-induced diabetes: involvement of oxidative stress